You've never heard of combo fix?! i'm not even sure if you're joking or not!
Its always my 'last resort' but I cant use it remotely because it kicks me off. I say last resort because it comes with a stack of warnings about its potential to mess up the comuters it scans but thats never happened to me before. Im no expert on it but i think it specialises in rootkits and cleaning infected windows files that are being used at the time of scanning. I've seen it delete infected system files and then automatically download clean ones from wherever it does. I usually find it gets rid of the malware that everything else couldnt, check it!
ComboFix | freeware