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07 Mar 2012  

Win7 Ultimate x64 7601

What software is it?
Sometimes, if you unpack the ISO to hard drive, then install the software from the location you unpacked to, it won't ask for a cd/dvd to run.

Or try a different image mounter, many of them like powerISO and such don't do too good a job at pretending to be a real DVD drive.
Give Damon Tools Lite, or Alcohol 52% a try.
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