OK. Looks like 4 drives, with each having 1 partition.
You want to clone C to E.
C is 69 gigs, with 9 free. E is 279 gigs, virtually all free.
I have used Acronis for imaging and have read what I can on Acronis cloning. I have NEVER actually cloned with Acronis.
Looks to me like you should not have any issues.
You might want to defrag C before starting.
Go to Acronis, locate the cloning tool, choose automatic, then choose source and destination drive. These come up on successive screens. I have not gone beyond this point in my exploration of my own version of Acronis.
The next screens probably concern partitioning and you may be asked if you want to delete partitions on the destination drive. I’m not positive whether you should say yes or no and I’m not sure it matters in this case.
If you make the wrong choice, you could just redo it.
I’d guess one choice might leave you with a 69 gig partition on the new drive (which you wouldn’t want) and the other might give you a 279 gig partition on the new drive, which you would want.
Even if you make the wrong choice, you should be able to boot the new drive and then expand the 69 gig partition to 279 gigs with Windows 7 Disk Management, without using Acronis.
My best guess would be to tell Acronis to NOT delete partitions on the destination drive, hoping that it then just leaves you with about 60 gigs of occupied space on a 279 gig partition.
Don’t mess with or delete anything on the current C until you are satisfied that all went well.