You're lucky I can't even get my (paid) Macrium to backup and
verify (which is the critical step) any image. If the image doesn't pass verification then the image isn't any good.
The reason you are getting that message is because the external My Book is still using the computer. You can do one of 2 things, turn the My Book off using the tab on the back (right above the USB cable) or you can go to the right corner in the notifications bar (over where the clock and stuff is) and there should be a tab that says "safely remove hardware"; click on that and you can unplug it. It will reinstall the
driver the next time you reconnect it. Personally I just shut mine off. You can also power down (turn off) the PC then turn the My Book off using the tab above the USB. That keeps the
driver installed. With this method you just turn it back on before the next reboot.