I assume that you are attempting to clone
to, not
from, the new drive.
Therefore the filesystem problem would be at the source, which I assume to be your Windows drive or C: partition.
I would suggest opening a DOS command window and entering the following command:
You should then be told that the drive cannot be locked, and if you'd like to run the check at the next reboot. Answer yes, then restart your PC. chkdsk will run shortly after the PC starts booting into Windows and then reboot again to go back to Windows.
This should fix most, if not all filesystem errors. After that you can try cloning again - also, in Macrium you can disable verifying the filesystem before starting the backup process.