Trust me, I tried all sorts of things to get it to work. I've been working (off & on) on the effing problem since Friday. But, yes, I tried typing in msn.com, looking it up on Google and clicking the link from there, clicking on other msn pages and then clicking the home link on those pages... and they all gave the same result. Even reverted back to IE9 and was getting the same issue.... so it's not exclusive to 10.
At any rate I finally got it working by reinstalling java, you never know, and clearing/deleting my cookies and other stuff including active x and stuff (yay I get to re-sign into all my forums and stuff again).
I also restored and reset the setting here, though I've never messed with them in the first place....
Anyway it's working for now; but it did the same thing Friday when I uninstalled IE10, then promptly reverted back to the issue, even without 10 installed. That said, I'll see how long this lasts this time. Fingers X'd