I have 2 Radeon 5870 cards running in CrossFire. I have to temporarily disable CrossFire when I run ONLY one modded game S.T.A.L.K.E.R: Call of Pripyat Complete Mod, vanilla runs with crossfire without any issues.
After I finish playing this game I go back to Catalyst Control Centre and re-enable crossfire and on 2 occasions my computer showed BSOD and rebooted.
I have Catalyst Control Centre 11.4 preview edition, this is unsigned driver
meaning not certified by Microsoft.
I have not tried to disable/re-enable crossfire while using older drivers
because there was no need for that.
This is how it happens, I open CCC select Performance | AMD CrossFire Configuration | check crossfire and click apply. Then screen goes black and fan revs up for a few seconds then it shows a portion of my desktop which appears to be cut up into little pieces and finally it causes my computer to reboot. Most of the time when I re-enable CrossFire it acts the same way except that it does not crash.
I never experience any issues while running the game, no lock ups, no BSODs (knock on wood). I will attach .DMP file.