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Kim Peek - TelegraphHoffman's portrayal of a middle-aged savant's complex interaction with the world through astonishing mental facilities and childlike emotions earned him an Oscar for best actor. But it was Peek, who suffered from Agenesis of Corpus Callosum (a condition similar to autism), whom Hoffman and Barry Morrow – Rain Man's writer, who also won an Oscar – acknowledged as the inspiration behind the performance.