I use it on several machines. If you want to play with it, go to the high performance beta software. There is software for 32 and 64 bit and even GPU's.
Be aware that it can run your CPU at up to 100% and it may cause some software to run slower even though it is not intended to. It is intended to replace the 'System Idle Process', and make use of 'unused' processor cycles. It will cause your system temperatures to rise.
But it's a good cause, and I run a few clients at work where I am allowed to and the machines are on 24/7 anyway. And I run a few clients at home. I have been participating for quite a while.
Installation advice and help can be found here: Folding Forum Index page