New
#11
Is this close to what you are looking for: (For Vista but might work in 7 too.)
How to Delete Old User Profile Folders Automatically in Windows Vista - The Winhelponline Blog
http://support.microsoft.com/kb/940017
Edit, BTW just deleteing C:\Users\[username] while does remove the profile, it doesn't remove the registry entries. It kinda confuses the profile service into thinking the profile is corrupted.