I run a Windows 7 RC (64Bit) Build 7100 Version (German).
So far all Programms & Games just work fine.
The only problem i had was with my Creative Live! Cam Vista IM (VF0420).
I downloaded on the creative website the latest vista 64 bit driver
& and programm (called creative live cam center). But when trying to install them, combatibility probs showed up.
Then i found a thread on this Forum how to run a programm in combatibility mode (right click on driver, choose properties and then compatibility. Now you can choose a different OS).
But what i did, is even easier. Right click on driver and click on "troubleshoot compatibility". Now Windows looks for the problem itself and recommended XP SP2 mode (in my case). Confirm. Driver is being installed and settings are saved.
Now it works just fine.