I read in another forum that for some reason, this mouse can be disabled by pressing the caps lock button twice too quickly. I had the same problem as the original poster, and was disheartened when my roommate called to tell me that the mouse had stopped working. I read some forums and found this fix. Windows had been reading the mouse as "malfunctioned" and would not install it after disconnecting, replugging, and restarting. Anyway, this did it and my mouse is good as new. OCZ must have had some crazy design thoughts when they designed a mouse with an automatic feature to disable the mouse without telling anyone