It doesn't really matter what kind of specs you have, some games are simply not designed to be alt-tabbed to Desktop and back. There was a time when readme's included such information.
However, if you were able to do this earlier and started seeing problems recently, it may probably have something to do with the graphics
drivers. Still, it's not recommended you do this with games in any case.
In Skyrim, for example, switching between the game and the desktop multiple times will simply shut the game down, no errors or crashes or anything.
The Saboteur needs a few seconds to reload certain textures before it runs smoothly again, while games like Bulletstorm (if I remember correctly) will simply not let you get back into the game at all. Just a few examples I've witnessed.