I'm usually able to solve any video game issue I have, and have gotten just about every game I play to work flawlessly on windows 7 64bit except this one.
The error I'm getting is this one, and yes, the dvd is in the drive.
I'm running on a fresh install (courtesy of getting fallout3 to work), and have tried the following:
Compatibility mode (vista, vista w/ admin, xp, xp w/admin)
Re-installed on c: drive, then on d: drive.