If you have updated hardware, 64bit capable, there are no "issues" with Vista 64bit.
To run Vista 32bit, if you really wanted it to hum, may have needed, in many cases, a little cash spent on better graphic capabilities and, possibly, more ram. 64bit was a slightly bigger step and more expensive - it would have required a look at your motherboard/CPU among other things. There we get into the area of buying a whole new computer
I have a computer which runs 32bit perfectly. Although it is "64bit capable" It struggles with 2gbs of Ram and an antiques ATI 9600 pro graphics card - but it works, I dual boot.
Like so many others (I'm a pensioner!) I do not have the budget, at the moment, to spend cash on the needed upgrade.
It should be pointed out, however, that the software (excluding
drivers) is not a problem. I have 39 programs which I migrated from XP to Vista 32bit. I have never had a problem with them. Ditto, the same programs installed on the 64 bit version, in the x86 directory, and also run 100%.