I would recommend the following....
We will start with this first,
Just incase, you might want to backup any data you don't want to lose if something is really going wrong....
AVG =
Uninstall it and never go back. (if I could triple underline and double bold that I would)
Then as suggested run SFC \Scannow ,, could be a good idea to do this now.
however, I might not suggest this if it is infact malware or virus related.
The choice is yours.
Run the following on-line scanners....
Run both of these one at a time till complete.. Very important.
What's new - Windows Live OneCare safety scanner for Windows Vista and Windows 7 Free ESET Online Antivirus Scanner
Then yes, Install
Malwarebytes as suggested and run that....
If anything is found,, clean it as needed (clean, quarantine, delete, whatever is needed)
Then run them again till nothing is found in each.
If something is found, but can't be cleaned, then there are other issues to worry about.
I would then install MSE and try scanning and cleaning with that.
Post anything that is found and can not be got rid of.
If everything comes back clean or is cleaned.
Then run SFC /Scannow
Install
MSE
You may need to reinstall Live Mail,,, but I would do that later after doing what is listed above.
Then we can see what else might be going on.
Database files being created like that could be caused by malware or virus.
Or a corrupt application or OS.