Windows 7 - Folder automatically closes after 5-10 minutes

This has been so frustrating. When I open a folder (usually a desktop folder) after maybe 5-10 minutes the desktop flashs (icons reload) and the folder closes without warning. Very annoying having to reopen time after time while I'm working with the contents in the folder. I have tried virus scans, reset folder options and several other 'suggestions' without any success. Everything else works fine i.e. browser and programs. This has been going on for about 2 weeks. Any ideas anyone?

Thanks in advance.

Did you try malwarebytes? Please download and run this:

Malwarebytes : Malwarebytes Anti-Malware PRO removes malware including viruses, spyware, worms and trojans, plus it protects your computer

Also, check for rootkit:

Sophos Anti-Rootkit - Free Rootkit Detection and Removal Tool

Thanks Lemur. Sophos didn't find anything but Malewarebytes found several problems. Fixed everything and nice to have my computer back. Thanks again for your help.

Glad it worked. Good luck!