Thank you for your replies!
Brink > Actually, the folders and files are not system files and are not necessarily located on the system drive. They are on my personal drives both internal and removable. A typical pathname might be, "d:\My Files\Latest Projects\RCOM\Figure1.jpg". None of the these files were ever set to read-only nor can any of the checkboxes be made to be unchecked. They always revert back to checked.
Also, all rights and permissions are Admin and I am logged in as Admin.
sibbel > No, all folders and files in all the paths are read/write.