Windows 7: RPC errors and non-responsive programs when adding another HD

Hi. I'll try to be brief. I've looked online many times and cant seem to find anyone else experiencing the same problem as me.

My PC is running Windows 7 Ultimate 64-bit. I have several HD's inside (2 drives configured in RAID0, and two Green Drives for storage).

Problem: For some strange reason, when I attach a particular hard drive from my other PC to use it as storage, the Windows on this PC starts acting up. Basically what happens is that when launching My Computer, windows gives a RPC error, and many of my programs stop working, such as Firefox. I can fix the RPC error manually by starting the service, but my programs not working cannot be fixed. The only solution is to shut 'er down, disconnect this hard drive, and boot up without it. Then, magically, everything is back to normal.

For the record, no, there is nothing wrong with the drive I'm attaching. It too has Win 7 64-bit installed on it, and works great in it's own PC. In fact, I use it everyday, without any issue. A couple of other things to note, yes, I'm booting the correct OS, no viruses on either PC or HD, no malware, no anti-virus software. No special partitions, or file systems. Just a case of Windows acting stupid when connecting this particular drive for the purpose of storage and transferring of large files.

Feel free to submit your thoughts as to why my Windows is so bothered from attaching this drive.