Absolutely not. Only CCleaner is safe to scan the registry. All others will mess it up.
Run a full scan with Malwarebytes
. In addition I'd run SUPERAntiSpyware.com - Downloads
which really roots out the spyware that can take over. After install run a full scan then Clean Up anything it finds, uninstall it or turn it off starting with windows by unchecking all the boxes in preferences.
Establish a Clean Boot as given in the Troubleshooting Steps you should already be working through.
Make sure nothing except Flash, .pdf helper, WMP or QT player plug-in is in your browser add-ons.