Deleting Content.IE5 content

I have about 83GB of useless data trapped in C:\Windows\system32\config\systemprofile\AppData\Local\Microsoft\Windows\Temporary Internet Files\Content.IE5\Z1O6OK0R, DQ1O7FJH, etc. This is not to be confused with C:\Users\Owner\AppData\Local\Microsoft\Windows\Temporary Internet Files. The only way I could examine them is by using the Glary Utilities Diskspace analyzer. Using Windows explorer I could not get past systemprofile. When I try to delete the files with the analyzer nothing happens. All the tips I have read seem to refer only to the C:\Users string. Double clicking on Z1O6OK0R, etc reveals all of the saved pages, many thousands of them. How do I get rid of them and reclaim the space again?

I did the reveal hidden folders thing. CCleaner only cleans out the C:\Users string. I have run it and several other cleaners, but none of them touch these files. They just remain there.