I know it might be a bit late, but I have the same problem as jpwilli3. I have Windows Task Manager start minimized when Windows start (using WinPatrol), but some processes are missing their Description (and presumably Usernames, but I removed that column). This is on a new and clean Windows 7 Professional 64-bit installation. I am 99% sure that this isn't virus related, since it has been this way from the beginning.
I previously had Windows 7 Pro 32-bit on my old laptop, but I never had this problem.
I did notice that if I exit the task manager and reopen it, all the descriptions are loaded. This led me to believe that perhaps a Windows service has not started yet, so on a new restart I opened services.msc immediately to see which services have not started yet. However, when I opened services.msc, all the descriptions in task manager show, once I opened it.
So, in conclusion, when task manager is started for the first time, the process descriptions aren't showing. When I close and reopen it, they show. If I open services.msc and then start task manager, they show.
Does anyone have any suggestions whatsoever? Do any other people have this problem?
Also, sorry for the long post.