I have something similar to this, I have a ATI Radeon HD 4800 Series card.
When I had my TV hooked up, I would sometimes have this issue where my mouse icon would first glitch up, then it would normally crash but sometimes it would come out of it's glitch. If it continued, I had no BSOD, but the screen did turn blue and started strobbing between a pattern of blue blocky colors, nothing would happen it could sit there all day, until I restarted it.
I realized this had something to do with my extra display and it was a TV on S-Video, and I had it positioned to the South East corner of my monitor to get to it, so this problem would happen when I went to show the desktop or went to look at the time, since my mouse would jump onto the extra display (being the tv).
I have disabled my tv since I dont use it much, but haven't had the problem since.
I could though use my tv and go back and forth between it, but it was just this weird thing that would happen when I didn't want it to