New
#1
Its usally fine to just leave as it is as even viewing hd content is pretty easy for a 460 so no matter what you put it on it shouldnt affect it, maybe give it prioty over other programs, putting it all on max/quality wont hurt tho.
With ccc i just let the appliction choose.
I higly doubt with a system like that it will make any difference what settings you choose as it is quite high powered.
Your running a hi end rig so setting it to quality is a no brainer..I just let NV auto detect and set itself to w/e it feels like.
Applications like games I use the ingame settings to set whatever.... which is normally pretty much maxx everything, and as long as it doesnt make the FPS drop to low then that's what I use.