Yes. The easiest way to do it is to clone the hard drive with C: to the new drive. There are several products to do this, but if one of your drives is a Western Digital or Seagate (maybe other HDD manufacturers as well) you can go to the drive manufacturers support site and download a special edition version of True Image Home. This has the capability to make a clone of one drive to another and it is fairly straight-forward. Basically you do the clone operation, shut down your computer, remove the old drive and connect the cloned drive to where it was (or swap them), and boot it up.