The Radeon 4850 is a DirectX 10.1 card, not DX 9.
Did you uninstall the AMD (ATI)
drivers before swapping garphics cards? That's recommended, even though you're replacing one AMD card with another. (Re-install the
drivers after the new card is in place.)
A 500W or higher power supply is recommended for a 6870. You don't say what sort of PSU your 450W unit is, but if it only has a single 6 pin PCI-E power connector, it may not be a high-end 450W one. (They're not all created equal.)
Hav you run a memory test on your upgraded system? If you mixed RAM from different manufacturers (or even ram of different specs from the same manufacturer), you might be having compatibility issues. If you replaced all the RAM, the new RAM could be defective. (That happens, even for highly reliable makers.)