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#11
since you are talking of a laptop, maybe the touchpad is interfering somehow. I already had a less-than-stellar touchpad that keeps thinking someone is using it and screws navigation of a USB mouse someone is actually using.
Try disabling the touchpad (should have a Fn key or from Device Manager). Also is the touchpad driver updated? Usually their specific drivers are smart enough to shut down the thing when there is a USB mouse (or offer that as an option), but I cannot speak that well of MS generic ones.
Also check if touchpad is dirty or shows damage (use it and check if some areas of it don't work).
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