Windows can't stop your 'Generic volume' device

Hotswap! didn't work either. I already have that on my PC.

System restore and recycle bin were already disabled for those drives.

Callender said:

Any luck with stop explorer - eject drive - restart explorer?

Other thoughts: Copy files elswhere and format the drive. Copy the files back.

It's just the one drive correct? Will check this thread tomorrow and see if anyone else has ideas.

This happens with several drives in a couple of my external enclosures, so it's not limited to just 1 drive.

I haven't tried explorer yet because I have already rebooted my PC and turned off my enclosure, so currently it's not on and locked for me to try it. I'll give that a try tomorrow.

I wonder if this happens in Safe Mode.

Also would a clean startup help? Troubleshoot Application Conflicts by Performing a Clean Startup

If you don't mind losing current Restore Points, turn it off for all drives. Don't forget to create a manual Restore Point after trying this one if you do.

How about your anti-virus? Can it be scanning the partition?

GokAy said:

I wonder if this happens in Safe Mode.

Also would a clean startup help? Troubleshoot Application Conflicts by Performing a Clean Startup

If you don't mind losing current Restore Points, turn it off for all drives. Don't forget to create a manual Restore Point after trying this one if you do.

How about your anti-virus? Can it be scanning the partition?

If it was my anti-virus, wouldn't "what's locking my file" tell me it was the antivirus that was locking it? Plus, I'm using Avast now, but last year I was using Avira, and this has been happening for years. It's just getting more annoying now as more of my external enclosures are USB3.