***A little background on why my drive dissapeared. I was getting a corrupted file error prior to my enclosure dissapearing. The file conatined some pictures. When I ran chkdsk in windows, it failed. I did a search on the error I was getting (something about "can't access file because it's corrupt" which means you can move it bu not delete it) I found no help other than to run chkdsk. When I ran chkdsk, it failed on the corrupted file and my drive dissapeared, but only for eSATA connections, not USB.***
Last night I went home and shut down my computer. I then hooked up the external enclosure to my eSATA port again and turned it on. I booted my PC and went into BIOS. The external showed up there and I verified it was not the boot drive. I exited BIOS and hit F12 to pick the boot menu anyway. Again, it was my C: drive, so I let the boot continue. Windows 7 Startup splash screen appeared, and right before the log on screen, it went into DOS mode and started a chkdsk of my eSATA enclosure. Sure enough, it located the previously mention corrupted files, deleted all the logs associated with them, then restored my files to original! After that, it proceeded to continue to the logon screen. When I logged on, I clicked on My Computer and sure enough there was my drive! I browsed it and I was able to access the previously corrupted file just fine. I guess the chkdsk utility runs differently in DOS mode than actually in Windows. I was able to run my back up program and write to the drive and everything. There must have been some corrupt system files in the file tables that the computer didn't like via eSATA? I don't know exactly.