Mmmmaybe, I haven't seen what the EXE extracts. Probably an ISO (But you can install an ISO mounter and run it from there)
HOWEVER. Things will be a lot easier and safer if you just burn a DVD or make a bootable USB drive and install it that way...
Also, just to be safe, always disconnect all hard drives but the one drive you want to install to and boot from before doing the install. This'll prevent the boot files from accidentally being installed on the wrong drive or other potential install headaches.