Well if a reboot is not needed then you could run devcon.exe via a batch file for a one click solution to disable multiple devices. You could also do this then reboot but that would be a pain.
You can find devcon.exe on Google but it might be a old version that won't work on Windows 7 or you can get it from the Windows Driver Kit
but that's a large download.
There's also a chance you already have it somewhere on your computer as I did. I found it was included in the install of Slysoft Virtual Clonedrive
which is a tiny download but does require installing to access the file which can then be copied to where ever you like before uninstalling Virtual CloneDrive. It was also included with one of my device drivers.