If you are doing a Upgrade than Yes Try to get Nero off..
Here is also a Tutorial of how to Upgrade with Windows 7 Upgrade Install with Windows 7
But if you are doing a Clean install, (which you can with an Upgrade Disk
) You could just backup your data, then boot from the disk and install that way..(and that will get rid of Nero and everything else for that matter)
Here is another Tutorial of how to do a clean install with an Upgrade Disk. Clean Install with a Upgrade Windows 7 Version
Hope this Helps..