Can only access internet in safe mode

Hello,

Our computer can no longer access the internet. It thinks it's connected and reports no problems on diagnostics, but is saying "error code: connection refused"

I can access internet in safe mode

I have:

Ran malware bytes and super anti spyware in safe mode. It found a few things and removed them. Still no internet access.

Restored the computer to the 25th, it was working then.

Disabled windows firewall and all other firewalls

Ensured that the box was unchecked and blank in LAN settings on ie explorer

I have tried ie, chrome and Firefox

Uninstalled the latest windows update. The problem occurred right after the update.

Updated internet driver

I'm at a loss

Welcome to the Seven Forums.

I don't have a Vista OS to test things on at the moment, but I'll help as best I can. Most things should be the same as on W7

You might want to try the steps mentioned here:
Troubleshoot Application Conflicts by Performing a Clean Startup

It would help us to help you if you could fill out your system specs:
System Info - See Your System Specs
and post the info for item #6 from here:
Basic Requirements Before Posting your Networking Thread
(we don't need the Wi-Fi info)