The problem with IE10 is that there are many file types it refuses to run for security reasons.
This is giving me fits when doing things like trying to update my routers firmware which does not work with IE10, I also can't use my .gws file to reinstall my routers settings. I've also noticed that IE10 will not even download a gadget file, I'm using the RP so I still have my gadgets.
I may be sticking to IE9 for a long time to come on my Windows 7 machines.
The security on these new browsers is great but when you can no longer do basic tasks it's time to rethink what the hell we are doing here.