You can use McAfee as your first scan if that's what's on your computer. But I would still recommend using at least a couple more on-demand scanners starting with Malwarebytes. As I said, no product is 100% effective 100% of the time. If there was such a product we'd all be using it.
If McAfee doesn't find any problems,
definitely try the on-demand scanners. If McAfee DOES find problems,
definitely use a couple of the on-demand scanners to make sure McAfee didn't miss something.