Sounds like you are trying to defrag system reserved partition, this is a very small partition reserved on the HDD with your boot info and some windows recovery options in there hence why there is no drive letter assigned to it, if this is the case its best left well alone, it should only be 100MB in size and defragalyzing it will do nothing, and if you frag it up your comp wont boot
If your not sure or dont understand post a snip of your disk management window
Start>diskmgmt.msc