Do you mean that on the right half of your monitor, the cursor disappears and won't return when you mouse back over to the left side of the monitor? Or if you mouse it off-screen to the right, it won't return?
Also, please fill out your System Specs so we can better assist you.
My Computer
Computer type
PC/Desktop
OS
Windows 7 Pro x64 SP1
CPU
AMD Phenom II x6 1090T Black Edition 3.2GHz
Motherboard
ASUS M4A88TD-V EVO/USB3
Memory
Patriot G ‘Sector 5’ Edition 8GB (2 x 4GB) 1600MHz
Sound Card
(onboard) Realtek® ALC 892 8-Channel High Definition Audio
Monitor(s) Displays
ViewSonic VX2253 22"
Screen Resolution
1920x1080
Hard Drives
Transcend SSD720 2.5" SATAIII 64GB SSD; Western Digital Caviar Green WD20EARS 2TB 64MB 3.5" HDD
LG WH10LS30 10X Blu-ray Burner with LightScribe
PSU
CORSAIR TX Series 950W ATX12V 80 Plus Bronze
Case
Cooler Master HAF X NVidia Edition; 5 Green LED Fans!
Cooling
CORSAIR A70 120mm Dual-Fan
Keyboard
Verbatim 97472 Mini Wireless Slim
Mouse
bundled Verbatim 97472 Wireless
Antivirus
Avast
Browser
Chrome
Other Info
Ultraportable/Desktop Replacement Laptop:
circa Oct 2006,
Dell XPS M1210,
Windows 7 Professional 32-bit,
Intel Core 2 Duo T7200 2.0GHz,
3.25 (4) GB of RAM,
NVidia GeForce Go 7400,
500GB Seagate Momentus 7200RPM HDD