Files that I can delete off of Main HD directory

I am terribly sorry if I posted this in the wrong place. I couln't really find a catagory that this could go under. This is the closest.

I am cleaning out my HD, I am at the main directory and I know deleting certain files (such as C:\Windows) would screw up the system. There is tons of files in the main C:\ directory and I don't know which are ok to delete.

List of Names:

3e50f5fd1498e47a140a2ee50acdd6
7aca77941baca13e237058
77da4204ca352de59e9005f1be7bf688
91b34cd87cb7caf91979
adobeTemp
cb614aa5a887a5c2319dd2c4
DVDMovie
DVDTemp
EFI
found.000
Hotfix
IExp0.tmp
IExp1.tmp
Intel
PerfLogs
Python27
SnowFiles

Those are all directory that I have no clue what they do. I didn't include files. I also did not include folders that I know what there purpose (Program Files ect). Any help would be highly appreciated!

Ccleaner will help some, it won't remove program folders but it will remove excessive system files/temp files
I don't suggest using it's registry feature but the file cleaner works great. (make sure to check the app tab and click the chrome/firefox options if you use those browsers.
I would not delete any of the folders you list there, the strange list of numbers are usually associated with a .net framework installer, or a system update. I wouldn't remove any of them until I knew exactly what they were and that removing them would not cause application problems.
CCleaner - Download