No idea really about Luks, but I used TrueCrypt somewhat and found it to be very good and convenient, I can recommend using it. But in any case, the best you can do is to try both yourself and check what you do like more.
My Computer
Computer type
Laptop
Computer Manufacturer/Model Number
Toshiba Sattelite A665-S6092
OS
Windows 7 Ultimate x64
CPU
Intel Core i7-740QM
Memory
8 GB DDR3
Graphics Card(s)
NVIDIA GeForce 330GT
Screen Resolution
1366x768
Hard Drives
Samsung 840 SSD 500GB
1TB USB3 external HD
Cooling
Coolermaster Notepal U3 notebook cooling pad
Internet Speed
3mbps ASDL
Antivirus
ClamWin 0.98.7
Browser
Opera 12.17 x86 (main), Firefox 38 (sec), IE11 (last resort)