TuneUp Utilities during the Windows 98/ME/XP days was a good utility to have, it actually did what it was advertised to do, with todays OS's with mose of the features of TuneUp Utilities already built into the OS it's really is not needed and besides TuneUp Utilities these days is nothing short of bloatware and will do more harm to your computer than good.
I stopped using it mostly after switching from XP to Vista, it gave my system more errors than I care to remember, tried it once on Windows 7 and wound up with BSOD after running it, I just trashed the program after that, I would not recommend the program to anyone runnning Vista and above.