Windows 7: Repeating fatal errors with .NET Framework

Has anyone had this issue before?

I use a POS program called Wireless Standard for work, we recently had to upgrade it and as soon as I did. Whenever I try and open it I get the the following error:
Google results state its an issue with the .NET Framework and more then one being installed.
If I try to repair it or re-install it (after uninstalling), it will start rolling back and I'm met with Installation Log States: So after looking this up its supposed to be because of a corrupt installation. I've tried installing with the full installer as well as the web installed of .NET Framework. and I get the same issue.

Now the only way that I can get it to work, is if I rename the .NET Framework assembly folder, and then install it afterwards..
Problem is that if I restart the computer at all after i install it (or it restarts because of the windows updater), the CLR error: 80004005 starts all over again.

Has anyone else had this kind of issue?
When I spoke to technical support for the program that we're using they said, that it might be an issue my computer. And i should reformat it, problem is that I just cannot do that I have to many things on it that I can not delete (including certificates).

I've tried adding a new user on it too and its the same problem.



Any suggestions?