Hello RockStar, you tried the .exe and .lnk registry but nothing worked ? If so, I would suggest you to try
Troubleshoot Application Conflicts by Performing a Clean Startup first, and see if it works.
If not, Try to run the desired program by double clicking it. Now open task manager , right click on the task bar and select "start task manager" from the context menu, go to the processes tab and see if that program is running or not. Most probably it is there.
If not, you may need to reinstall the program.
If yes, kill the program in task manager, try to set the windows basic theme and try to open the program again . Does it work now ?