No idea really about Luks, but I used TrueCrypt somewhat and found it to be very good and convenient, I can recommend using it. But in any case, the best you can do is to try both yourself and check what you do like more.
Computer type Laptop System Manufacturer/Model Number Toshiba Sattelite A665-S6092 OS Windows 7 Ultimate x64 CPU Intel Core i7-740QM Memory 8 GB DDR3 Graphics Card NVIDIA GeForce 330GT Screen Resolution 1366x768
Cooling Coolermaster Notepal U3 notebook cooling pad Hard Drives Samsung 840 SSD 500GB
1TB USB3 external HD Internet Speed 3mbps ASDL Antivirus Kaspersky Antivirus 2013 Browser Opera 12.15 x64