I can report i had issue's with Nod32 V4.0.437 (64bit version). Basically windows would boot up and within 30 seconds the whole system would lock. Not a full lockup though. Mouse would still move and such, i just couldn't open any windows.
So i tried a slightly lower version (That i'm still running now) V4.0.314 and i've not had a single problem with it.
But the first/higher version i tried could of just been a bad file/install or something. Anyway i've been a user of Nod32 since it's release and it's never let me down yet. It's said to be the gamers choice and that's good enough for me