I have a Sonar studio (and learning Pro Tools).
Depends on what recording DAW (program) you are using and how it detects the sound devices. I had a SoundBlaster installed and as it has an ASIO
driver Sonar would always pick that up as the default sound device when I started Sonar, rather than my recording device (either an MAudio Fastrack Ultra 8R or a Focusrite Saffire Pro 40). I could reset the defaul audio device in Sonar to either of my interface units but it was a minor hassle so I replaced the SoundBlaster with a different PC sound card that did not have an ASIO
driver and that took care of the problem. I still had a PC sound card but when I started Sonar it only recognized whichever recording interface unit (the MAudio or Focusrite) that I had powered on and wanted to use.
However, if you only have a version of Pro Tools that will only work with their (Avid/Maudio) devices then the SoundBlaster won't be a problem as it will ignore it. As I noted I'm learning Pro Tools and have Pro Tools MP9 version and the "M" version will only work with Avid/MAudio devices and will not recognize other devices.