I think you will have better luck getting this solved over here: Official ESET Support Forum - Wilders Security Forums
I used to use Nod32... it took me weeks to get its many, many, many settings just right for it to work without interfering with other things, it is definitely not a user-friendly AV because it does take a LOT of trial and error just to get it setup. Anyway, there should be some kind of tutorial on that forum somewhere that will help you get the settings right and that's going to be your best bet at fixing this.
When I used it (two years), I wasn't ever getting any viruses... it wasn't detecting or altering me to anything, and never found squat. So I decided to get rid of it when my license ran out and it turns out that I didn't really need such a powerful AV because I don't get viruses - I get maybe ONE a year and when I do, if MBAM can't knock it out (very rarely ever happens) I then back up my crap and wipe the system out and we're good to go again. I prefer this to paying through the nose for a program that's just going to be a pain in the butt 365 days of the year, as opposed to only having to have one crappy day of backing up and restoring the system when the "big one" hits lmfao.