Now that you mention it, two of my gadgets would not launch (Well they launched but never appeared on screen) last night after installing it a day or two ago.
BUT that has happened to me before, BUT I have not seen it happen in the last few weeks. If it continues to do so, MSE will be the 10th AV program I've installed unnecessariy found not one single thing wrong and eventually uninstalled when it starts causing problems I never had before. They are frequently as bad as having a virus anyway
(Before I get asked again, no routine AV use in 15 years and not one virus ever, safe computing is easy, Just Do It)