1. surf from an SUA/LUA account only
2. set UAC to max
3. set DEP for all
4. use MSE for A/V
5. on demand only scanners- Malwarebytes, superantispyware, eset free on line, emsisoft, hitman pro.
6. Most important part.........Sandboxie.......never open your browser without it.
7. with whats going on in the world, it might be a good idea to concider staying away from software which comes from countries about to enter a civil war ie: Europe.