I recently had the moneypak FBI virus and cleaned my registry using Ccleaner and also cleared my Temp files manually (which actually got rid of the problem).
Since I cleared this, the top left hand corner of my screen (roughly 2 icon squared in size) does not allow any direct clicking or interaction. The area is not obstructed by any objects and I can still drag things out of that area as long as my cursor is on an area outside of said area.
This affects all programs I use, including my browsers, Steam and Explorer.
I realise I have probably deleted a registry file I shouldn't have but have had no luck finding any other people who have had the same problem, any help you guys can offer would be most appreciated! Cheers!