Hi Gary,
don't think we need another UAC thread

What I think it does show is the need for a malware regime which is as up to date as is possible and maybe relies on Heuristics rather than lists of "Virus Signatures" as so many of these viruses will be "new" and not in a list. The problem with with heuristics is the amount of "False Positives" it generates. It's a very fine line for the AV companies to walk to make an application which catches the new malware without annoying the user too much, (that they switch it off or change to another,possibly less effective, less intrusive product).
I personally have a setup that, as far as I know, works but I am still willing to look at other options as because the malware changes and companies update their products the "best" Anti virus/spyware application will change